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Cat. No. Product Name Target Signaling Pathways
T2309 Ganetespib

STA-9090

Apoptosis; HSP; HIF Angiogenesis; Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism
Ganetespib (STA-9090) 是一种热休克蛋白 90 抑制剂,通过抑制 HIF-1α 和 STAT3 对大肠癌具有抗血管生成作用。它还具有细胞毒性。
T71426 STA-1474

STA-1474 is a water soluble prodrug of ganetespib (formerly STA-9090). STA-1474 will metabolized to Ganetespib, which is a potent HSP90 inhibitor previously shown to kill canine tumor cell lines in vitro and inhibit tumor growth in the setting of murine xenografts. The purpose of the following study was to extend these observations and investigate the safety and efficacy of STA-1474 in dogs with spontaneous tumors.

化合物

Ganetespib
Cat.No: T2309
Synonym: STA-9090
Target: Apoptosis, HSP, HIF
STA-1474
Cat.No: T71426
Synonym:
Target:
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